Prion Diseases, Softcover reprint of the original 1st ed. 2017
Neuromethods Series, Vol. 129

Language: English

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Prion Diseases
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105.49 €

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Prion Diseases
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This volume provides comprehensive information and detailed laboratory protocols used in the study of prion diseases. The chapters in this book cover topics such as: electron microscopy, neuropathology, immunohistochemistry, and immune-gold electron microscopy of prion diseases. Chapters also provide readers with detailed information about kuru, the clinical description of prion diseases, and the detection of prion protein and biomarkers. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.

Cutting-edge and authoritative, Prion Diseases is a valuable resource for researchers and scientists in the exciting and rapidly growing field of prion disease research.

Series Preface...
Dedication...
Preface...
Table of Contents...
Contributing Authors...

1.     Kuru: Introduction to Prion Diseases
Paweł P. Liberski, Agata Gajos, and Beata Sikorska

2.     Anthropological Methods used in Kuru Research
Shirley Lindenbaum

3.     Nonhuman Primates in Research on Transmissible Spongiform Encephalopathies
David M. Asher, Pedro Piccardo, and Luisa Gregori

4.     Clinical Features and Diagnosis of Human Prion Diseases
Richard Knight

5.     Neuropathology, Immunohistochemistry, and Biochemistry in Human Prion DiseasesDiane L. Ritchie and James W. Ironside

6.     Sub-Cellular and Molecular Changes Associated with Abnormal PrP Accumulation in Brain and Viscera of Classical a
nd Atypical Prion Diseases
Martin Jeffrey and Gillian McGovern

7.     Electron Microscopy of Prion Diseases
Paweł P. Liberski

8.     Cell Death and Autophagy in Prion Diseases
Pawel P. Liberski 

9.     Methods for Isolation of Spiroplasma sp. from Prion Positive Eye Tissues of Sheep Affected with Terminal Scrapie
Frank O. Bastian

10.  Detection and Diagnosis of Prion Diseases using RT-QuIC: An  Update
Byron Caughey, Christina D. Orru, Bradley R. Groveman, Matilde Bongianni, Andrew G. Hughson, Lynne D. Raymond, Matteo Manca, Allison Kraus, Gregory J. Raymond, Michele Fiorini, Maurizio Pocchiari, and Gianluigi Zanusso

11. Analysis of Charge Isoforms of the Scrapie Prion Protein using Two-Dimensional Electrophoresis
Elizaveta Katorcha and Ilia V. Baskakov

12.  Exosome
s in Prion Diseases
Alexander Hartmann, Hermann Altmeppen, Susanne Krasemann, andMarkus Glatzel

13.  Synthetic Mammalian Prions
Fabio Moda, Edoardo Bistaffa, Joanna Narkiewicz, Giulia Salzano, and Giuseppe Legname

14. Biomarkers in Cerebrospinal Fluid
Joanna Gawinecka, Matthias Schmitz, and Inga Zerr

15.  The Use of Transgenic and Knock Out Mice in Prion Research
Abigail B. Diack and Jean C. Manson

16.  Transgenic Mouse Models of Prion Diseases
Julie Moreno and Glenn C. Telling

Includes cutting-edge methods and protocols

Provides step-by-step detail essential for reproducible results

Contains key notes and implementation advice from the experts

Includes supplementary material: sn.pub/extras