Description
Translating Biomaterials for Bone Graft
Bench-top to Clinical Applications
Coordinators: Ong Joo L., Guda Teja
Language: EnglishSubjects for Translating Biomaterials for Bone Graft:
Keywords
Bone Graft; Bone Graft Substitutes; therapy development pipeline; Bone Void Filler; bone therapy; Recombinant Human BMP-2; clinical uses; Plaster Of Paris; pre-clinical studies; MSCs; materials properties; Bone Graft Extender; translational research; Calcium Phosphate Cements; bone tissue engineering; Synthetic Bone Grafts; Teja Guda; Joo Ong; Tissue Engineering; Translating Biomaterials for Bone Graft; ACS; Allogenic Bone Grafts; Bone Regeneration; Synthetic Bone Graft Materials; Autologous Bone Graft; Alveolar Ridge Augmentations; BMP-2; Bioactive Glass; APC; Bone Graft Alternatives; Posterolateral Lumbar Fusions; Spine Fusions; Composite Scaffolds; BMP-2 Gene
Publication date: 03-2021
· 15.6x23.4 cm · Paperback
Publication date: 12-2016
· 15.6x23.4 cm · Hardback
Description
/li>Contents
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Translating Biomaterials for Bone Graft: Bench-top to Clinical Applications brings together the current translational research in bone tissue engineering, from design to application ? from materials, drugs and biologic delivery used for bone graft applications to pre-clinical and clinical considerations. The book also discusses the regulatory approval pathways, which involves consideration of the class of devices; whether they are similar to existing solutions, minimal manipulation of donor tissue or completely novel materials, drugs and biologics. These considerations drive the ability to successfully transition the latest generations of bone graft materials into the clinics. Chapters come from materials scientists, clinicians, researchers, and consultants and provide a holistic understanding of the field. As such, the book is a state-of-the-art reference to bone therapies and should appeal to clinicians, scientists, as well as students interested in the current research and/or practices in the field of bone regeneration and restoration.
Editorial Foreword.Introduction. Bone Grafting Evolution. Materials. Ceramics. Polymers. Composites. Currently available grafts on the market. Growth Factors. BMP-2 and BMP-7. Other growth factors and delivery mechanisms. DBM and grafts. Cells and Biologics. Cell sources for orthopaedic defects. Cell sources for craniofacial defects. Animal Models for regeneration. Infection and antibiotics. Clinical Perspective. Orthopaedic Trauma. Spinal reconstruction. Dental and craniofacial reconstruction. Regulatory and ease-of-use