Description
Epigenetics and Complex Traits, Softcover reprint of the original 1st ed. 2013
Coordinators: Naumova Anna K., Greenwood Celia M.T.
Language: EnglishSubjects for Epigenetics and Complex Traits:
Keywords
Support: Print on demand
341 p. · 15.5x23.5 cm · Hardback
Description
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Part I: Epigenetic phenomena in the germ line and early embryonic development and their effects on the inheritance of genetic traits.- Epigenetic reprogramming in the mammalian germ line.- Establishment of tissue-specific epigenetic states during development.- X-chromosome Inactivation.- Cis- and trans-effects underlying polar overdominance at the callipyge locus.- Transgenerational epigenetic effects and complex inheritance patterns.- Autosomal monoallelic expression.- Part II: Epigenetic variation in health and disease.- Recurrent CNVs in the etiology of epigenetic neurodevelopmental disorders.- Impact of the early-life environment on the epigenome and behavioral development.- Interaction between genetics and epigenetics in cancer.- Part III: Impact of epigenetics on complex trait genetics and analysis.- Epigenetic variation, phenotypic heritability, and evolution.- Statistical Approaches for Detecting Transgenerational Genetic Effects in Humans.- Transmission ratio distortion: a neglected phenomenon with many consequences in genetic analysis and population genetics.- Epigenome Wide Association Studies: Potential insights into human disease.- Analytical Considerations for Epigenome-wide Association Scans of Complex Traits.- Index.
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